Telomeres implications and current research essay

The Affinity Argumentexplains that invisible, immortal, and incorporeal things are different from visible, mortal, and corporeal things. The lengthening of life expectancy is mainly due to the elimination of most infectious diseases occurring in youth, better hygiene, and the adoption of antibiotics and vaccines.

Epinephrine is secreted from the adrenal medulla in response to low blood glucose, exercise, and various forms of acute stress in the latter case, the brain stimulates release of the hormone.

Supporting this hypothesis is the evidence that animals living in a protected environment eg, a zoo live longer, potentially reaching their maximum life spans Holliday All these fundamental examples suggest the importance of quadruplex structures in cell processes and their understanding may provide better insight into aging and disease development.

Supporting the hypothesized relationship between telomeres and aging, it has been demonstrated that some telomere dysfunctions are involved in the premature aging characteristic of progerias.

In particular, Franceschi identified the macrophage as the primary modulator of the vicious cycle existing between innate immunity, inflammation and stress. Aging should then be considered as the result of a decrease ability Telomeres implications and current research essay survive stress, suggesting once more the close relationship between stress and longevity.

In fact, oxidative modifications have been shown to occur in of DNA, protein, and lipid molecules Weinert and Timiras Helicase proteins act as unzippers, to separate intertwined strands of DNA into single strands for such purposes as to allow transcription, replication and recombination.

It is defined by the reduction in caloric intake while maintaining essential nutrient requirements. Thus, stress, whether physical i. Although the epidemiological data are overwhelmingly positive regarding some health benefits of estrogen replacement therapy, a recent study has raised a concern about ovarian cancer after long-term use.

Therefore, Sikhs have a similar belief of immortality of reincarnation like the hindus, but they belief there is way that we could get out of being rebirth and death, by doing the good deeds that the all the ten gurus have left behind for them to do.

The best outcome, Kagan argues, would be for humans to live as long as they desired and then to accept death gratefully as rescuing us from the unbearable tedium of immortality. Some drugs that are already approved for other uses have been studied for possible longevity effects on laboratory animals because of a possible CR-mimic effect; they include rapamycin[69] metformin and other geroprotectors.

In response to hypothalamic signals, the hypophysis produces and secrets several hormones acting in the regulation of many important functions of the body.


Other strong and highly informed intellectual contributors have joined me in researching and authoring materials for the blog, Jim Watson in particular as a very strong partner.

Moreover, flies selected for increased longevity have elevated levels of superoxide dismutase and increased resistance to oxidative stress Arking et al In pursuing a solution to these issues, we should keep clear in mind what Hayflick wrote in a Nature commentary: Although some hormone replacement strategies have been shown in clinical trials to modify some of physiological attributes associated with aging, negative side effects occur frequently with those interventions shown to have some benefit, such as growth hormone.

Scientists find way to increase length of human telomeres

Given how much there is yet to learn about such important areas, can adding understanding of G-quadraplexes be so important as to be worthwhile. Human telomeres are attached to the nuclear matrix. If you want to learn about the forefront areas of the health and aging sciences, I suggest reading the blog entries.

Alterations of the biological clock eg, reduced responsiveness to the stimuli regulating the clock, excessive or insufficient coordination of responses would disrupt the clock and the corresponding adjustments Finkel ; Timiras ; Weinert and Timiras Free Radic Biol Med.

They are extremely strong drugs. By about mid I was updating this treatise only selectively and somewhere in the middle of I gave up doing that completely except for listing blog entry links.

Heat can affect their coming and going, and their presence near promoter elements can block gene activation. From an evolutionary perspective, mammals and their ancestors have already undergone several hundred million years of natural selection favoring traits that could directly or indirectly favor increased longevity, and may thus have already settled on gene sequences that promote lifespan.

Finally, it remains to be seen whether such new tissue even if it were autologous would be adequately vascularized and subsequently function appropriately in the patient.

In this context, the search for a single cause of aging such as a single gene or the decline of a body system has recently been replaced by the view of aging as an extremely complex, multifactorial process Kowald and Kirkwood ; Weinert and Timiras They require their own specific anti-neurotic treatment and not mere oral magnesium physiological supplementation, but both genuine forms of neurosis due to primary neural magnesium deficiency and magnesium depletion secondary to a neurosis may exist.

Another hypothesis argues that free radicals cause aging because of the accumulation of oxidized proteins in cells. This regulation is controlled by the release of hormones eg, growth hormone, oxytocin, vasopressin or by the stimulation of peripheral endocrine glands eg, adrenal cortex, thyroid, gonads.

This greatly increases the number of cells available for studies such as drug testing or disease modeling. Neverthelss, the free radical theory of aging seems to be the one receiving the widest acceptance as a plausible explanation of the primary chemical reactions at the basis of the aging process De La Fuente Many non-oncogene promoters also form G-quadruplexes.

Illustration from Hinduism Today, Hindus believe in an immortal soul which is reincarnated after death. Several and important step forward the understanding of the aging process have been done, so that it is no more an obscure issue of biology Holliday Evolutionary theory of aging Evolutionary theory indicates aging as the result from a decline in the force of natural selection.

The alleged benefits of the treatment, none of which have been demonstrated in a proper study, include a longer life, darker hair, better memory, better sleep, curing heart diseases, diabetes and Alzheimer.

Now, researchers from the Stanford University School of Medicine, CA, say they have found a way to lengthen these telomeres, potentially opening the door to new treatments for many age-related and genetic conditions.

Litteratur Psykopati, Narsissisme, Selv, Abnormal Psykologi, Tilknytningspsykologi, Neuropsykologi, Vitenskapelig metode, Vitnepsykologi, Utviklingspsykologi mm. Essay on Telomeres: Implications and Current Research Words 5 Pages At the core of every organism lies a particular cellular alphabet which encodes the information for the lifelong development and maintenance of that organism.

Free Biology papers, essays, and research papers. Practical Applications of Evolutionary Biology - Charles Darwin and Alfred Wallace's concept of natural selection and descent with modification helped shape the theory of evolution which holds as much weight as the theory of relativity per se.

Evolutionary biology is the science devoted to understanding. Researchers from the Stanford University School of Medicine have created a novel technique that they say can increase the length of human telomeres by up to 10%.

Magnesium for Depression: A Cure for Depression using Magnesium?

Beyond just being loaded with “artery-clogging saturated fat” and sodium, bacon has been long considered unhealthy due to the use of nitrates and nitrites in the curing process.

Many conventional doctors, and well-meaning friends and relatives, will say you’re basically asking for a heart attack or cancer by eating the food many Paleo enthusiasts. Current Research on Duchennes Muscular Dystrophy Essay - Current Research on Duchennes Muscular Dystrophy Duchenne's muscular dystrophy is the result of a defective gene on the X chromosome.

This gene is responsible for production of the muscle protein dystrophin.

Telomeres implications and current research essay
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